Biological sequence searching identifies unique DNA, RNA, or protein sequences in patent and scientific literature to assess novelty. Keyword searches often miss relevant results, making tools like STN and BLAST essential. This process requires specialized database expertise.

The major elements of a bio-sequence

Bio-sequence Input: Searches begin with a FASTA-formatted sequence representing nucleotides or amino acids, often containing multiple sub-sequences (e.g., heavy chain regions in antibodies).

Search Algorithms & Databases: Specialized algorithms and scoring matrices match input sequences using free databases like GenBank, SwissProt, PIR, and commercial tools like STN and Questel Orbit.

Matching Criteria: Users define parameters such as sequence identity, query coverage, and sequence length based on the search objective.

What will our bio-sequence search report cover?

• Identified results containing sequences relevant to the client's input
• Alignment details including identity percentage, similarity, and query coverage
• Extracted claims and text from matching references
• Bibliographic details of the identified references
• Insights to support R&D, legal, and strategic decision-making

Jurisdictions covered

• Worldwide
• United States (USPTO)
• Europe (EPO)
• World Intellectual Property Organization (WIPO/PCT)
• China (CNIPA)
• Japan (JPO)
• Korea (KIPO)
• India (IPO)
• Other target markets of interest (according to client business strategy)

Report Outline

• A typical bio sequence search report contains:
• Project overview
• Relevant references
• Search Strategy and Search Log
• Technology Segmentation and Keyword Taxonomy
• Assignees’ and Inventors’ Details
• Legal Status Overview

Why is Biological Sequence Search required by companies and R&D?

• Identifies known sequences to assess novelty for patents and research
• Predicts function by matching unknown sequences to known ones
• Supports FTO and IP strategy by detecting potential infringements
• Aids in genetic engineering through selection of suitable sequences
• Enables biosimilar development by comparing with reference biologics

How Business Benefits from Biological Sequence Search?

1. Protects Innovation – Confirms sequence novelty, enabling strong patent applications and exclusive rights for genes, proteins, or constructs.
2. Minimizes Legal Risk – Supports freedom-to-operate (FTO) analysis to avoid infringement and lawsuits before product launch.
3. Accelerates Development – Identifies similar known sequences to speed up discovery, design, and testing, especially in pharma and biotech.
4. Enables Competitor Benchmarking – Analyzes patented and published data to track competitor activity and spot market gaps.
5. Supports Regulatory Compliance – Helps demonstrate similarity with approved biologics, crucial for biosimilar approval.
6. Opens New Markets – Detects species- or disease-specific sequences for developing targeted agricultural, medical, or environmental products.

Methodology

1. Understanding Technology: Define project objectives and technology domain.
2. Keyword-Based Search: Conduct comprehensive patent searches using keywords, classification codes (IPC/USC/CPC), assignee/inventor names, citation analysis, and similarity searches on databases like Orbit, Totalpatent, Patseer, Derwent Innovation, Google Patents, and Espacenet.
3. Sequence-Based Search: Perform sequence searches using free public databases (NCBI BLAST, Patent Lens) and/or commercial databases like REGISTRY on STN.

Deliverables

It include an Excel report with:

• Project overview and methodology
• Relevant references with sequence alignment, identity, query coverage, and bibliographic details
• Search logs detailing search strategies and strings used.

Why Us?

At Effectual, we have successfully delivered 500+ Bio-sequence worldwide in various branches of science for gathering and analyzing the latest advancements and innovations in specific scientific fields such as biotechnology, Pharma etc.

As a leader in IP services, we bring proven expertise, cutting-edge technology, and a commitment to your success.

• Highly Qualified Team
• Effectual Keyword and Standard Search Tool
• Access to Comprehensive Databases
• Comprehensive Search Strategy
• Enhanced Search Capabilities
• Tailored Solutions
• Empowering Innovation

Explore Our Sequence Listing Services

FAQs

Q1: What is a bio-sequence search, and why is it significant?

A bio-sequence search is a specialized procedure that is utilized for analyzing and comparing biological sequences like DNA, RNA, or proteins. It plays a significant role in many domains like genomics, drug development, and molecular biology to identify genes, regulatory regions, functional motifs, etc. This analysis helps researchers interpret genetic information and molecular mechanisms, resulting in scientific advancement.

Q2: How can bio-sequence search services benefit my research or project?

Our bio-sequence search services are really a fantastic tool. They allow you to identify the biology sequences that are of interest to you, they help you to compare the sequences to the known ones, find the functional elements, and even develop an experiment or therapeutic molecule. If you are a person who is into the academic field, studying biotechnology, or the one who is involved in pharmaceuticals, these are the probable ways in which our services are going to help you.

Q3: What kinds of bio-sequence searches do you provide?

We offer a broad array of bio-sequence search services, ranging from sequence similarity searches to motif discovery, gene annotation, and structural analysis. We customize our services to address your individual research needs, so you get personalized solutions for your project.

Q4: Is my data confidential throughout the process of bio-sequence search?

Yes, we place a high premium on data security and confidentiality. Your research data is treated with the highest degree of care and professionalism, and we have very strict confidentiality agreements in place to safeguard your intellectual property.

Q5: How long does a typical bio-sequence search project take?

Project duration completely depends on the complexity of the search and the number of data, as well as on your specific requirements. On our side, we impact the project duration positively by clearly setting the timeline and at the same time employing the shortest possible way to get the job done.

Q6: Will you provide patent searching using bio-sequences?

Absolutely! Our bio-sequence search services also involve patent examination, for example, prior art searches, Freedom-To-Operate, Infringement, and patent landscape studies. We assist you in the identification of prior patents related to your innovation and the assessment of patentability.

Q7: Which kind of clients are suitable for your bio-sequence search services?

We serve a variety of clients, such as academic researchers, biotechnology organizations, pharmaceutical companies, healthcare facilities, and so on. We customize our services to suit the specific requirements of each client.

Q8: How can I get started with your bio-sequence search services?

Do not worry about it. One way of getting started with our bio-sequence search services is to get to the contact us section this web page using our phone number or the inquiry form. After that, we will be able to find a suitable time for a consultation and talk about your project requirements, goals, and timelines. After that, we will recommend a solution that will fit your needs.

Q9: Do you provide support for interpreting bio-sequence search results?

Actually, we do provide support for the interpretation as well as utilization of the results of bio-sequence search in an efficient way. We aim to give you all the information and the knowledge to make your studies and projects more productive.

Q10: What sets your bio-sequence search services apart from others in the field?

Our services are set apart by the use of the most advanced bioinformatics tools, the availability of experienced professionals who can customize solutions, and our adherence to strict confidentiality and data security. Our commitment is to the delivery of good quality work that stands to bring innovation in the fields of genomics, drug discovery, and molecular biology.