Insulin plays a crucial role in regulating blood sugar levels in our body. Without sufficient insulin or when the body becomes resistant to its effects (as in type 1 and type 2 diabetes, respectively), blood sugar levels can become dangerously high, leading to various health complications. People with Type 1 and Type 2 diabetes needs Insulin therapy to maintain their insulin level and avoid any serious illness. There are various types of insulin devices available to help individuals with diabetes such as:

Insulin Syringes, Insulin Pens, Insulin pumps, Insulin Patch pumps, Jet Injectors, Inhaled insulin, Insulin vial Adapters, etc. These devices are very useful for their users however for those who are using it for the first time, kids and those who are afraid of invasive methods are a little hesitant and maintaining these devices regularly could be an issue. Therefore there has been a growing demand of non-invasive insulin administration solutions. Some major key factors for this trends being:

Improved Patient Comfort, Enhanced Convenience, Reduced Fear and Anxiety, Improved Adherence, Reduced Risk of Infection and Skin Issues, Ease of Use for Elderly or Physically Impaired Individuals, Less Training and Education Required, Improved Quality of Life, Privacy and Discretion, Technology Advancements, Patient Preferences, etc. Based on the above factors a lot of medical device companies are trying to develop new and novel non-invasive insulin administration solutions. However there are certain challenges with their development faced by these companies such as:

· Achieving accurate and reliable insulin delivery

· Skin Barrier Permeability

· Biocompatibility and Safety

· Duration of Action and Consistency of Delivery

· Dosing Flexibility/Patient Variability

· Device Design and Miniaturization

· Regulatory Approvals and Clinical Outcomes, etc.

We were approached by one of the companies to solve one such challenge by looking at all promising developments made in this space. And here's how we solved this challenge-

Objective:

The objective of the study was to identify novel and breakthrough solutions for Non-invasive insulin administration.

What we did:

The mechanical and medical device research analyst team of Effectual did a QnA with groups doctors and the principal fellows from the company and identified some key question that we tried to answer in our findings:

1. What are the novel/innovative technologies for non-invasive insulin administration to the body? Are these safe to use or do they have some

limitations for use? Do these technologies provide good bioavailability for insulin?

2. What are the various routes of administration of insulin through non-invasive methods? Which is the best and safest route of administration among all? In which form of insulin, the delivery through non-invasive administration is the most effective?

3. What are the various benefits that Non-invasive procedures/products provide over conventional solutions? What are the various significant parameters that contributes to the success of non-invasive insulin administration?

4. Are these technologies available at the commercial scale or these are present at the small scale? Which of these technologies are still available at the research phase? Is there any clinical study available for the innovative non-invasive insulin administration technologies?

5. Which key players are working in the space? What challenges they are facing and what solutions are available for these challenges?

6. What are the key success market stories that can be seen as market drivers?

Based on the above questions the team created a framework to list potential solutions. The framework included parameters based on Applications, regulatory approvals, clinical trials, proof of concepts, market availability, timeline, patent protection.

Execution Strategy: The project was completed under 8 weeks. During the execution process, 2 interim discussions were also scheduled with the client to get their feedback on the ongoing work and ask for any additional recommendations.

Study Outcome: Our research team was able to identify 23 novel recommendations where each solution was evaluated and presented in details with technical details, clinical testing and results, citation trees, market trend, cost, supply chain, etc.

If you wish to know more about such work, please feel free to email us at info@effectualservices.com or visit our website www.effectualservices.com